Federal agencies are ramping up defenses against a tiny but devastating threat to America’s food supply: the New World Screwworm. In an unprecedented simulation exercise conducted earlier this month, homeland security officials played out nightmare scenarios of this flesh-eating parasite crossing U.S. borders.
The Department of Homeland Security’s Office of Health Security, working alongside USDA, CDC, and the Department of Interior, conducted the two-part exercise in January with 80 in-person and more than 170 virtual participants from federal, state, local, and tribal authorities.
“Food security is national security. I want to thank Secretary Rollins and Secretary Burgum for recognizing that and taking action to protect the American people,” said Secretary Kristi Noem. “A country that cannot feed itself and provide for itself cannot defend itself. We need to protect America’s food supply to protect the American homeland.”
Preparing for the Worst
The simulation wasn’t just theoretical disaster planning. With the parasite already causing havoc to the south, officials tested three specific invasion scenarios: illegal cattle smuggling, spread via wild animals, and introduction through a human carrying an infested wound.
“This is the first exercise of its kind,” noted Dr. Sean Conley, Acting DHS Chief Medical Officer and Acting Director of the Office of Health Security. “The sessions provided participants with a shared operational baseline and an opportunity to test coordination and identify decision points critical to an effective government response.”
Why the sudden urgency? The situation across the border has deteriorated rapidly. The CDC has reported more than 1,190 human cases and seven deaths from New World Screwworm in Central America and Mexico as of January 20. The outbreak has steadily moved northward into northern Mexico, putting U.S. agricultural interests on high alert.
A $100 Million Challenge
The federal government isn’t just planning for disaster — it’s putting serious money behind prevention. The USDA announced a New World Screwworm Grand Challenge on January 21, offering up to $100 million for innovative projects to enhance sterile fly production and prevent northward spread of the parasite.
“This is a strategic investment in America’s farmers and ranchers and is an important action to ensure the safety and future success of our food supply, which is essential to our national security,” said Secretary Brooke Rollins about the initiative.
The stakes couldn’t be higher. As of January 27, over 149,000 animal cases have been documented across Central America and Mexico. The U.S. has so far confirmed just one human case — a traveler returning from El Salvador — but the fly itself hasn’t been detected on American soil.
That single human case serves as a stark reminder of the parasite’s gruesome nature. New World Screwworm flies lay eggs in open wounds, and the resulting maggots feed on living flesh, potentially causing death if untreated.
Racing Against Time
The multi-agency approach reflects growing recognition that traditional borders between animal health, human health, and national security have blurred. Agencies that once operated in separate silos are now coordinating closely.
Could this be the new normal for America’s biosecurity landscape? Many experts think so. Climate change has expanded the range of tropical parasites and pathogens, while global travel and trade create new pathways for their spread.
For now, the focus remains on keeping the screwworm at bay through surveillance, preparedness, and innovation. But the simulation exercise reveals an uncomfortable truth: in today’s interconnected world, the next agricultural disaster might be just one smuggled cow or returning traveler away.

